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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAC1
All Species:
48.79
Human Site:
T125
Identified Species:
82.56
UniProt:
P63000
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P63000
NP_008839.2
192
21450
T125
D
L
R
D
D
K
D
T
I
E
K
L
K
E
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001109586
205
22986
T138
D
L
R
D
D
K
D
T
I
E
K
L
K
E
K
Dog
Lupus familis
XP_855587
192
21504
T125
D
L
R
D
D
K
D
T
I
E
K
L
K
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q05144
192
21422
T125
D
L
R
D
D
K
D
T
I
E
K
L
K
E
K
Rat
Rattus norvegicus
Q6RUV5
192
21432
T125
D
L
R
D
D
K
D
T
I
E
K
L
K
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513560
192
21428
T125
D
L
R
D
D
K
D
T
I
E
K
L
K
E
K
Chicken
Gallus gallus
Q90694
191
21254
T125
D
L
R
D
D
P
S
T
I
E
K
L
A
K
N
Frog
Xenopus laevis
NP_001084224
192
21460
T125
D
L
R
D
D
K
D
T
I
E
K
L
K
E
K
Zebra Danio
Brachydanio rerio
NP_956065
192
21516
T125
D
L
R
D
D
K
D
T
I
E
K
L
K
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40792
192
21335
T125
D
L
R
D
D
K
N
T
I
E
K
L
R
D
K
Honey Bee
Apis mellifera
XP_623951
192
21451
T125
D
L
R
E
D
K
E
T
I
E
R
L
K
D
K
Nematode Worm
Caenorhab. elegans
Q03206
191
21436
T125
D
L
R
E
D
R
D
T
V
E
R
L
R
E
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38912
198
21710
F128
D
L
R
D
D
K
Q
F
F
A
E
H
P
G
A
Baker's Yeast
Sacchar. cerevisiae
P19073
191
21304
I125
D
L
R
D
D
K
V
I
I
E
K
L
Q
R
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
88.2
99.4
N.A.
91.6
100
N.A.
92.1
70.3
99.4
98.4
N.A.
91.6
91.1
82.8
N.A.
Protein Similarity:
100
N.A.
88.7
99.4
N.A.
96.3
100
N.A.
95.8
82.2
100
100
N.A.
95.8
95.8
91.6
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
66.6
100
100
N.A.
80
73.3
60
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
73.3
100
100
N.A.
100
100
100
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
63.6
69.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
74.7
82.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
100
0
0
86
100
0
65
0
0
0
0
0
0
15
0
% D
% Glu:
0
0
0
15
0
0
8
0
0
93
8
0
0
65
0
% E
% Phe:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
86
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
86
0
0
0
0
79
0
65
8
72
% K
% Leu:
0
100
0
0
0
0
0
0
0
0
0
93
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
8
% Q
% Arg:
0
0
100
0
0
8
0
0
0
0
15
0
15
8
8
% R
% Ser:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
86
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _